Hearing Loss Prevention

Fennec is Focused on Helping Cisplatin-Induced Hearing Loss

Cisplatin is a highly effective treatment for testicular cancer. However, one of the side effects is ototoxicity or hearing loss which has a profound impact on quality of life.

Fennec Pharmaceuticals work in the Neuro-ototoxicity space for patients with solid tumors who are treated with cisplatin to reduce the risk of hearing loss.

NIH Research Study: Effects of ALA on Cisplatin-induced Ototoxicity

Research studies have suggested that ototoxicity induced by cisplatin is due to an accumulation of reactive oxygen species and oxidative stress. NIH found that Alpha-lipoic acid (ALA) an antioxidant, may have a protective effect on hearing loss induced by cisplatin.